Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) patients present with or without biochemical hyperandrogenism (HAPCOS or non-HAPCOS, respectively). Although cardiometabolic and hormonal abnormalities have been reported in women with PCOS, particularly those with hypertension, direct comparisons between normotensive (blood pressure (BP) <140/90 mmHg) patients with HAPCOS and non-HAPCOS are scarce. Data on N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) in PCO...

Introduction: Saliva is an interesting alternative to blood in clinical evaluation of endocrine function. Certain advantages of saliva collection must be considered, when comparing with conventional blood sampling. Vital arguments are that procedure is easy, non-invasive and stress-free. The studies on correlation between salivary and serum thyroid hormones are scarce and contradictory. The goal of our research was to assess if salivary thyroid hormone levels reflect serum con...

Introduction: Adropin, a newly discovered peptide hormone, seems to have broad implications in energy homeostasis and metabolism in humans. Its main role is in maintaining appropriate carbohydrate and lipid economy. However, the aim of this study was to look at the novel role of adropin as a potential marker for cardiac function and nutrition status in hemodialyzed (HD) patients. To the best of our knowledge, this was the first study to consider the relationship between serum ...

Introduction: Graves ‘Orbitopathy (GO), is an autoimmune disease associated with Graves’ thyrotoxicosis (GT). The therapy is largely dependent on the severity and activity of ocular changes. Additionally, the severity of GO is influenced by exogenous factors, such as thyroid dysfunction, cigarette smoking or radioiodine therapy (RIT). The aim of the study was to indicate how radioiodine therapy (RIT) influences on GO in smoking and non-smoking patients.<p class="...

Introduction: According to a limited number of specialized hospital beds for radioiodine therapy in some countries, fractionated dose of radioiodine may be considered as the ablation therapy of differentiated thyroid cancer (DTC). Aim of the study was to compare the late effects of ablation therapy with single and fractionated dose of radioiodine in patients with DTC.Patients and metods: Patients with DTC treated with one (131)I dose of 2.2 GBq or fracti...

Purpose: In the recent study it has been reported, that elevated serum concentrations of TSH receptor (TSH-R), antithyroglobulin (Tg), antiperoxidase (TPO) autoantbodies (Abs) may be observed in the subjects treated for amiodarone induced thyrotixicosis (AIT) type I, decreased in type II of AIT, or changed in amiodarone induced hypothyroidism (AIH). This study was done to analyse the changes of Tg-Abs, TPO-Abs and TSH-R-Abs titer in euthyroid, hyperthyroid (AIT), and hypothyro...

Introduction: Radioiodine (RAI) therapy is a standard procedure in therapy of hyperthyroidism. However, the use of RAI in euthyroid patients requiring chronic administration of amiodarone (AM), in a case of lacking efficacy of other antiarrhythmic drugs might be controversial.Objective: The aim of the study was to assess the safety and efficacy of an AM therapy prior to treatment with radioiodine therapy in euthyroid patients with permanent atrial fibril...

Introduction: According to the results of several studies and meta-analyses, certain ultrasound features are associated with increased risk of thyroid malignancy. However, most of those research papers included mainly papillary thyroid cancers (PTCs); these results cannot be simply extrapolated for the differentiation of follicular thyroid adenomas and cancers (FTAs and FTCs). The aim of the present study was to perform a meta-analysis of so far conducted research and identify...

Poland was considered as a mild-to-moderate iodine deficiency area according to results of a nation-wide survey conducted in early 1990-ties. The obligatory iodine prophylaxis program based on iodization of house-hold salt (30 mg of iodide/1 kg of salt) was therefore introduced in 1997.The aim of the study was to assess the real impact of the Polish iodine prophylaxis model on thyroid volume in schoolchildren.Material and methods: ...

Purpose: The aim of this study was to evaluate the association between the serum vitamin D level and changes in the titers of the anti-TSH receptor (TSHR), antithyroglobulin (Tg), and antiperoxidase (TPO) autoantibodies (Abs) in smoking cigarette Graves’ disease (GD) patients, with and without the vitamin D supplementation.Methods: The study was performed from January 2015 to December 2016. It consisted of 136 patients. The intensity of nicotinism w...